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The use of pharmaceutical intermediates

Organocatalysis uses small organic molecules predominantly composed of C, H, O, N, S and P to accelerate chemical reactions. The advantages of organocatalysts include their lack of sensitivity to moisture and oxygen, their ready availability, low cost, and low toxicity, which confers a huge direct benefit in the production of pharmaceutical intermediates when compared with (transition) metal catalysts.

In the example of the N-BOC-4-Hydroxypiperidine,it is believed that piperidine forms a reactive iminium ion intermediate with the carbonyl compound:


Description: N-BOC-4-Hydroxypiperidine
Synonym: N-(Tert-Butoxycarbonyl)-4-Hydroxypiperidine
CAS: 109384-19-2
Assay: ≥98% (GC)
Appearance: white or off-white  powder
Molecular:  C10H19NO3
Application: Pharmaceutical Intermediates

 

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